M Celeste Simon Selected Research

Oxygen (Dioxygen)

1/2022	Hypoxia-Inducible Factors in Cancer.
1/2021	Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection.
1/2020	Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.
10/2019	Even Cancer Cells Watch Their Cholesterol!
1/2018	Hif1α Deletion Limits Tissue Regeneration via Aberrant B Cell Accumulation in Experimental Pancreatitis.
1/2018	Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation.
1/2018	Myeloid Cell Hypoxia-Inducible Factors Promote Resolution of Inflammation in Experimental Colitis.
10/2017	Oxygen availability and metabolic reprogramming in cancer.
1/2016	Intratumoral oxygen gradients mediate sarcoma cell invasion.
7/2015	Oncogenes strike a balance between cellular growth and homeostasis.

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M Celeste Simon Research Topics

Disease

87	Hypoxia (Hypoxemia) 01/2022 - 04/2002
69	Neoplasms (Cancer) 02/2022 - 01/2004
14	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 01/2013
10	Renal Cell Carcinoma (Grawitz Tumor) 12/2021 - 09/2014
9	Carcinogenesis 01/2021 - 01/2005
8	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2004
5	Inflammation (Inflammations) 01/2020 - 01/2010
5	Polycythemia (Erythrocytosis) 01/2013 - 12/2007
4	Kidney Neoplasms (Kidney Cancer) 12/2021 - 09/2014
4	Ischemia 01/2017 - 01/2006
3	Infections 01/2021 - 01/2010
3	Neuroblastoma 01/2021 - 12/2010
3	Glioblastoma (Glioblastoma Multiforme) 08/2015 - 08/2014
2	Liver Neoplasms (Liver Cancer) 02/2022 - 01/2022
2	Liposarcoma 01/2021 - 02/2016
2	Fibrosarcoma 01/2021 - 06/2005
2	Lung Neoplasms (Lung Cancer) 11/2019 - 10/2010
2	Necrosis 01/2017 - 01/2013
2	Melanoma (Melanoma, Malignant) 05/2013 - 04/2005
2	Mitochondrial Diseases (Mitochondrial Disease) 06/2005 - 01/2005
2	Teratoma (Teratoid Tumor) 03/2005 - 12/2004
1	Hepatocellular Carcinoma (Hepatoma) 01/2022
1	Leiomyosarcoma 01/2021
1	Wounds and Injuries (Trauma) 01/2020
1	Bacterial Infections (Bacterial Infection) 01/2020
1	Starvation 01/2020

Drug/Important Bio-Agent (IBA)

46	Oxygen (Dioxygen)IBA 01/2022 - 01/2003
30	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2002
30	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2004
17	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 07/2003
12	EnzymesIBA 12/2021 - 01/2013
8	LipidsIBA 10/2019 - 05/2013
7	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 06/2004
7	Erythropoietin FDA Link 06/2011 - 01/2004
6	Small Interfering RNA (siRNA)IBA 01/2021 - 09/2008
6	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 02/2002
5	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2022 - 06/2004
5	Messenger RNA (mRNA)IBA 12/2021 - 06/2004
5	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2013
5	Glutamine (L-Glutamine)FDA Link 01/2021 - 12/2011
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2008 - 09/2004
3	GlycogenIBA 01/2021 - 09/2014
3	Fructose-BisphosphataseIBA 05/2020 - 09/2014
3	Glutathione (Reduced Glutathione)IBA 01/2019 - 10/2004
3	Mechanistic Target of Rapamycin Complex 1IBA 02/2016 - 09/2008
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2014 - 11/2008
3	Insulin (Novolin)FDA Link 10/2013 - 08/2003
3	Von Hippel-Lindau Tumor Suppressor ProteinIBA 05/2010 - 12/2007
3	TOR Serine-Threonine KinasesIBA 08/2006 - 08/2003
3	UbiquitinIBA 06/2005 - 01/2003
2	Urea (Carbamide)FDA LinkGeneric 12/2021 - 06/2018
2	CholesterolIBA 12/2021 - 10/2019
2	Phosphotransferases (Kinase)IBA 01/2021 - 06/2005
2	PPAR gammaIBA 01/2021 - 01/2018
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2017
2	Biological ProductsIBA 01/2021 - 01/2020
2	Inositol (Myoinositol)IBA 01/2018 - 05/2013
2	Indicators and Reagents (Reagents)IBA 02/2016 - 02/2009
2	epidermal growth factor receptor VIIIIBA 08/2015 - 08/2014
2	Carbonic Anhydrase IXIBA 03/2015 - 01/2013
2	Amino Acids FDA Link 12/2014 - 08/2003
2	CytokinesIBA 02/2014 - 07/2009
2	Glycoproteins (Glycoprotein)IBA 01/2012 - 04/2007
2	Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA 12/2010 - 04/2007
2	Ligases (Synthetase)IBA 05/2010 - 06/2004
2	Hormones (Hormone)IBA 11/2009 - 04/2007
2	Eukaryotic Initiation Factor-4EIBA 09/2008 - 09/2007
2	Cyclin D1IBA 09/2008 - 03/2005
2	Protein Isoforms (Isoforms)IBA 02/2007 - 05/2006
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 02/2006 - 08/2003
2	Adenosine Triphosphate (ATP)IBA 06/2004 - 08/2003
1	Glucagon (Glukagon)FDA Link 02/2022
1	Glucagon Receptors (Glucagon Receptor)IBA 02/2022
1	SenotherapeuticsIBA 01/2022
1	Arginine (L-Arginine)FDA Link 01/2022
1	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 12/2021
1	Argininosuccinate LyaseIBA 12/2021
1	NitrogenIBA 12/2021
1	Dietary CholesterolIBA 12/2021
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2021
1	Class Ia Phosphatidylinositol 3-KinaseIBA 01/2021
1	dihydrolipoamideIBA 01/2021
1	NAD (NADH)IBA 01/2021
1	Stem Cell FactorIBA 01/2021
1	IACS-010759IBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2020
1	GlutaminaseIBA 01/2020
1	IsoenzymesIBA 01/2020
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2020
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2019
1	Imatinib Mesylate (Gleevec)FDA Link 06/2018
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 06/2018
1	Pyridoxal Phosphate (Pyridoxal 5 Phosphate)IBA 06/2018
1	ArginaseIBA 06/2018
1	PolyaminesIBA 06/2018

Therapy/Procedure

21	Therapeutics 01/2022 - 06/2004
8	Drug Therapy (Chemotherapy) 01/2021 - 01/2014
3	Radiotherapy 01/2018 - 08/2009
1	Immunotherapy 01/2020